Plastics and Your Health

California Nurses for Environmental Health & Justice

An evidence-based look at how plastics and their chemicals enter our bodies, what they do to our health, and the science, laws, and resources behind the fight for a healthier future.s.

Plastics and Your Health title graphic

What Is Plastic?

Plastic is created from fossil fuels and chemicals. It consists of long molecular chains called polymers, made of strongly-bound monomers that don’t break down in nature.

More than 16,000 chemicals called additives are used to make those polymers usable and to transform plastic into the shapes and items we recognize.

Those chemicals can break down or leach out into our soil, our food, and the air we breathe.

Illustration of common types of plastic

Microplastics and Nanoplastics

Size classification of plastic particles

Plastic does not biodegrade — it breaks down into smaller and smaller pieces.

Plastic pieces are formed by the degradation of plastic waste, and they contaminate air, water, and food, and cross biological barriers—accumulating in human tissues and raising concerns about inflammation, cell damage, and long-term health effects.

  • Microplastics are visible pieces of plastic.
  • Nanoplastics are far smaller — invisible to the naked eye and small enough to interact with human cells.

The Plastic Life Cycle

  • Extraction & refining — fossil fuels refined into monomers like ethylene and propylene.
  • Manufacturing — monomers converted into resins, then formed into pellets, flakes, or products.
  • Distribution & usage — products are packaged and shipped; many are single-use.
  • Disposal — landfilled, incinerated (releasing toxic chemicals), or escaping into the environment.
  • Persistent environmental impact — plastic breaks down via UV rays into microplastics that contaminate soil and water, enter the food chain, and end up in the human body.
Diagram of the plastic life cycle

How We’re Exposed to Plastics

We’re exposed to plastics via three routes — each mapped to the graphic at left.

Three routes of plastic exposure: inhalation, ingestion, dermal contact

Inhalation — the respiratory barrier

We breathe in airborne microplastics; particles small enough bypass the lungs’ defenses and cross into the pulmonary blood vessels. (Pollution, dust, and synthetic fibers from clothes and furnishings.)

Ingestion — the gut barrier (most common)

Consumed via drinking water, seafood, salt, and food packaging; particles cross the intestinal lining into the lymphatic system and capillaries.

Dermal Contact — the skin barrier

From synthetic clothing, cosmetics, and personal care products; nanoplastics can pass through sweat glands and hair follicles to reach local blood vessels.

Health Impacts: Endocrine-Disrupting Chemicals (EDCs)

Once inside the body, nanoplastics are internalized by cells and cross epithelial barriers. They enter systemic circulation and travel to deep tissues, settling in organs like the liver, spleen, and brain.

Added chemicals leach out and mimic, block, or alter natural hormones (estrogen, testosterone, thyroid). Their presence triggers chronic inflammation and oxidative stress, altering major endocrine glands.

Illustration of endocrine-disrupting chemicals affecting the body

Body-Wide Health Impacts

Diagram of body-wide health impacts of plastic exposure

Respiratory, cardiovascular & GI

Inhalation and ingestion trigger systemic inflammation, oxidative stress, and cell damage—linked to lung tissue damage and a higher risk of heart attacks and strokes.

Immune system

As particles accumulate in immune organs, they interfere with macrophages, impair defenses against viruses and bacteria, disrupt the gut microbiome, and act as carriers for heavy metals, pesticides, and pathogens.

Reducing Plastic & the Recycling Myth

Most plastic isn’t truly recyclable — it is easily contaminated, chemically complex (16,000+ chemicals), degraded by processing, often higher in toxics once recycled, and economically unattractive.

Only a couple of resins are reliably reprocessed: #1 PET (water/soda bottles, jars) and #2 HDPE (milk jugs, shampoo & detergent bottles). #5 PP (yogurt/takeout tubs) is only conditionally accepted.

Illustration about the plastic recycling myth

Small Swaps, Big Impact

Infographic: swap plastic for healthier alternatives

Plastics in Healthcare

Illustration of plastic waste in healthcare

U.S. healthcare facilities produce 15,000 tons of waste daily — about 25% plastic.

  • Health risks: many devices contain PVC and additives like DEHP that can leach into patients.
  • Limited recycling: most waste is incinerated or landfilled, releasing chemicals linked to cancer, endocrine disruption, and infertility.
  • Single-use surge: an average of seven bags of plastic per patient.
  • Global injustice: waste is often exported to under-resourced nations.

Alternatives for Healthcare

Nurses can help reduce plastic consumption by:

Initiatives & resources: Global Green and Healthy Hospitals (GGHH), the Plastics Toolkit for Hospitals (HCWH SE Asia), and Sustainable Procurement strategies.

Illustration of sustainable healthcare alternatives

7 Groups of Harmful Chemicals

Ten groups of chemicals used to produce or enhance plastic are flagged as major human-toxicity concerns. Here are seven of the most significant. Overview: IPEN EDC brief; RSC, 2025.

Bisphenols (BPA, BPF, BPS)
Endocrine disruptor

Bisphenols (BPA, BPF, BPS)

Industrial compounds used to harden polycarbonate plastics and make epoxy resins for lining food & drink cans and thermal receipts. Endocrine disruptors linked to cardiovascular disease, obesity, type 2 diabetes, infertility, and neurodevelopmental issues.

Phthalates (DEHP, DINP)
Endocrine disruptor

Phthalates (DEHP, DINP)

Used to increase flexibility of plastics (especially PVC); heavily used in food packaging and clothing. Interfere with hormones; linked to reproductive harm, cancer, asthma, and heart-disease mortality.

Brominated Flame Retardants (BFRs)
Persistent

Brominated Flame Retardants (BFRs)

Organobromine compounds added to plastics like HIPS and ABS; used in electronics, black kitchen utensils, and toys. They leach and are found in dust, air, and recycled products.

PFAS & PFOA
Forever chemical

PFAS & PFOA

Make plastics water- and stain-resistant and improve durability; they don’t break down and accumulate in the environment and tissues. Linked to high cholesterol, thyroid disease, low birth weight, and kidney/testicular cancers; bioaccumulate up the food chain.

Dioxins & Furans
Persistent organic pollutant

Dioxins & Furans

Highly toxic POPs formed during manufacturing, bleaching, and incineration of plastics (PVC is a major source). They bioaccumulate and cause reproductive, immune, hormonal, and cancer effects. Over 90% of exposure is through food—meat and dairy.

Alkylphenols (APs)
Endocrine disruptor

Alkylphenols (APs)

Common variants (nonylphenol, octylphenol) protect plastics (especially PVC) and act as UV stabilizers. Endocrine disruptors linked to higher breast cancer risk and low sperm counts; they leach when heated.

UV Stabilizers
Endocrine disruptor

UV Stabilizers

Additives like benzotriazoles or HALS that prevent sun degradation; they don’t biodegrade and accumulate in tissue, blood, and milk. Endocrine disruptors linked to liver/kidney damage, immunotoxicity, neurotoxicity, and cancer.

California Legislation

California’s legislation to combat plastic pollution includes the Statewide Microplastics Strategy and Extended Producer Responsibility (EPR) requirements.

Plastic pollution (2022–2026)

  • SB 54 — Packaging Producer Responsibility Act (2022): shifts the burden from consumers to producers.
  • SB 1053 — Plastic Pollution Mitigation Fund (2026): expands SB 54.
  • SB 343 — Truth in Labeling Act (2022): limits the chasing-arrows symbol.

Microplastics & health

  • SB 1263 — Statewide Microplastics Strategy (2022).
  • DTSC Safer Consumer Products (2025): microplastics proposed as a Candidate Chemical.

Single-use & checkout bans